Anti-GBA antibody
| Name | Anti-GBA antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab55080 |
| Prices | $398.00 |
| Sizes | 100 µg |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Applications | WB IHC-P IHC-F ICC/IF ICC/IF |
| Species Reactivities | Rat, Human |
| Antigen | Recombinant fragment: SYFSEEGIGY NIIRVPMASC DFSIRTYTYA DTPDDFQLHN FSLPEEDTKL KIPLIHRALQ LAQRPVSLLA SPWTSPTWLK TNGAVNGKGS , corresponding to amino acids 146-236 of Human GBA Run BLAST with Run BLAST with |
| Description | Mouse Monoclonal |
| Gene | GBA |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
GBA antibody (ab55080) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human breast cancer.
ab55080 at 10 ug/ml staining GBA in human Hela cells by Immunocytochemistry/ Immunofluorescence.
All lanes : Anti-GBA antibody (ab55080) at 1/1000 dilutionLane 1 : Lysate prepared from MOCKLane 2 : Lysate prepared from human HN10 cellsLysates/proteins at 10 µg per lane.SecondaryIRDye® donkey polyclonal to mouse IgG at 1/3000 dilutionPerformed under reducing conditions.
Product References
Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating - Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating
Yang C, Swallows CL, Zhang C, Lu J, Xiao H, Brady RO, Zhuang Z. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):249-54.
Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked - Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked
McNeill A, Magalhaes J, Shen C, Chau KY, Hughes D, Mehta A, Foltynie T, Cooper JM, Abramov AY, Gegg M, Schapira AH. Brain. 2014 May;137(Pt 5):1481-95.
Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease - Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease
Tiscornia G, Vivas EL, Matalonga L, Berniakovich I, Barragan Monasterio M, Eguizabal C, Gort L, Gonzalez F, Ortiz Mellet C, Garcia Fernandez JM, Ribes A, Veiga A, Izpisua Belmonte JC. Hum Mol Genet. 2013 Feb 15;22(4):633-45.
Histone deacetylase inhibitors prevent the degradation and restore the activity - Histone deacetylase inhibitors prevent the degradation and restore the activity
Lu J, Yang C, Chen M, Ye DY, Lonser RR, Brady RO, Zhuang Z. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5. doi:
Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative - Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative
Lu J, Chiang J, Iyer RR, Thompson E, Kaneski CR, Xu DS, Yang C, Chen M, Hodes RJ, Lonser RR, Brady RO, Zhuang Z. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21665-70. doi: