Anti-Gelsolin antibody
| Name | Anti-Gelsolin antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab55070 |
| Prices | $359.00 |
| Sizes | 100 µg |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Applications | WB IHC-P ICC/IF ICC/IF |
| Species Reactivities | Human |
| Antigen | Recombinant fragment, corresponding to amino acids 673-783 of Human Gelsolin |
| Description | Mouse Monoclonal |
| Gene | GSN |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Gelsolin antibody (ab55070) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human adrenal gland.
ICC/IF image of ab55070 stained MCF7 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab55070, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.
Product References
Modification of the secretion pattern of proteases, inflammatory mediators, and - Modification of the secretion pattern of proteases, inflammatory mediators, and
Alvarez-Llamas G, Martin-Rojas T, de la Cuesta F, Calvo E, Gil-Dones F, Darde VM, Lopez-Almodovar LF, Padial LR, Lopez JA, Vivanco F, Barderas MG. Mol Cell Proteomics. 2013 Sep;12(9):2426-39.
Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's - Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's
Guntert A, Campbell J, Saleem M, O'Brien DP, Thompson AJ, Byers HL, Ward MA, Lovestone S. J Alzheimers Dis. 2010;21(2):585-96.