Anti-INPP4B antibody [EPR3108Y]
| Name | Anti-INPP4B antibody [EPR3108Y] |
|---|---|
| Supplier | Abcam |
| Catalog | ab81269 |
| Prices | $392.00 |
| Sizes | 100 µl |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone | EPR3108Y |
| Applications | WB IHC-P FC |
| Species Reactivities | Mouse, Rat, Human |
| Antigen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human INPP4B aa 1-100 (C terminal) |
| Description | Rabbit Monoclonal |
| Gene | INPP4B |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Immunohistochemistry analysis of formalin-fixed and paraffin-embedded human squamous cell carcinoma tissue sectioned at 4 μm and placed at 60°C for 1 hour. Slides were deparaffinized and antigen retrieval was carried out by microwaving the slides in Tris-EDTA buffer pH 9 at 650 W for 30 minutes. Samples were incubated with ab81269 (1/50) for 25 minutes at room temperature.INPP4B positive expression shows strong cytoplasmic staining. Magnification: X40.
Immunohistochemistry analysis of formalin-fixed and paraffin-embedded human squamous cell carcinoma tissue samples sectioned at 4 μm and placed at 60°C for 1 hour. Slides were deparaffinized and antigen retrieval was carried out by microwaving the slides in Tris-EDTA buffer pH 9 at 650 W for 30 minutes. Samples were incubated with ab81269 (1/50) for 25 minutes at room temperature.INPP4B negative expression. Magnification: X40.
Immunohistochemistry analysis of formalin-fixed and paraffin-embedded human skeletal muscle tissue (negative control) sectioned at 4 μm and placed at 60°C for 1 hour. Slides were deparaffinized and antigen retrieval was carried out by microwaving the slides in Tris-EDTA buffer pH 9 at 650 W for 30 minutes. Samples were incubated with primary antibody substituted for antibody diluent for 25 minutes at room temperature.Magnification: X40.
![All lanes : Anti-INPP4B antibody [EPR3108Y] (ab81269) at 1/5000 dilutionLane 1 : MCF7 cell lysate Lane 2 : Fetal skeletal muscle lysate Lane 3 : Fetal heart lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_3/8721_INPP4B-Primary-antibodies-ab81269-1.jpg)
All lanes : Anti-INPP4B antibody [EPR3108Y] (ab81269) at 1/5000 dilutionLane 1 : MCF7 cell lysate Lane 2 : Fetal skeletal muscle lysate Lane 3 : Fetal heart lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution
Immunohistochemical analysis of paraffin-embedded muscle tissue using ab81269 at 1/50 dilution.
Product References
PI3K pathway activation in high-grade ductal carcinoma in situ--implications for - PI3K pathway activation in high-grade ductal carcinoma in situ--implications for
Sakr RA, Weigelt B, Chandarlapaty S, Andrade VP, Guerini-Rocco E, Giri D, Ng CK, Cowell CF, Rosen N, Reis-Filho JS, King TA. Clin Cancer Res. 2014 May 1;20(9):2326-37.
Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with - Alterations of INPP4B, PIK3CA and pAkt of the PI3K pathway are associated with
Stjernstrom A, Karlsson C, Fernandez OJ, Soderkvist P, Karlsson MG, Thunell LK. Cancer Med. 2014 Apr;3(2):337-48.
Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy - Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy
Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmana J, Rajendran A, Papa A, Spencer K, Lyssiotis CA, Nardella C, Pandolfi PP, Baselga J, Scully R, Asara JM, Cantley LC, Wulf GM. Cancer Discov. 2012 Nov;2(11):1048-63.