Anti-KAT3A / CBP antibody - ChIP Grade
| Name | Anti-KAT3A / CBP antibody - ChIP Grade |
|---|---|
| Supplier | Abcam |
| Catalog | ab2832 |
| Prices | $391.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | WB ChIP IHC-P IP ChIPseq B/N |
| Species Reactivities | Mouse, Rat, Human, Primate |
| Antigen | Synthetic peptide corresponding to Human KAT3A/ CBP aa 162-176 |
| Description | Rabbit Polyclonal |
| Gene | CREBBP |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Sonicated chromatin prepared from U2OS cells was subjected to the ChIP procedure with ab2832 to CBP. Immunoprecipitated chromatin was analysed in the promoter region of c-FOS (active) and in exon 2 of MYO-D (inactive). Values are % of inputs. 2–4 µg of ab2832 and 1-2x106 cells were used in each ChIP experiment. Sergei Denissov, Prof. Henk Stunnenberg lab, University Nijmengen, NL
IHC image of KAT3A/CBP staining in human pancreas formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab2832, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.
Product References
Expression of p300 and CBP is associated with poor prognosis in small cell lung - Expression of p300 and CBP is associated with poor prognosis in small cell lung
Gao Y, Geng J, Hong X, Qi J, Teng Y, Yang Y, Qu D, Chen G. Int J Clin Exp Pathol. 2014 Jan 15;7(2):760-7. eCollection 2014.
Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone - Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone
Das C, Roy S, Namjoshi S, Malarkey CS, Jones DN, Kutateladze TG, Churchill ME, Tyler JK. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1072-81. doi:
Epigenetic modification of the leptin promoter in diet-induced obese mice and the - Epigenetic modification of the leptin promoter in diet-induced obese mice and the
Shen W, Wang C, Xia L, Fan C, Dong H, Deckelbaum RJ, Qi K. Sci Rep. 2014 Jun 13;4:5282.
The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. - The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth.
Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. Mol Cancer Ther. 2014 Oct;13(10):2303-14.
Akt kinase targets the association of CBP with histone H3 to regulate the - Akt kinase targets the association of CBP with histone H3 to regulate the
Liu Y, Xing ZB, Zhang JH, Fang Y. FEBS Lett. 2013 Apr 2;587(7):847-53.
C/EBPgamma suppresses senescence and inflammatory gene expression by - C/EBPgamma suppresses senescence and inflammatory gene expression by
Huggins CJ, Malik R, Lee S, Salotti J, Thomas S, Martin N, Quinones OA, Alvord WG, Olanich ME, Keller JR, Johnson PF. Mol Cell Biol. 2013 Aug;33(16):3242-58.
cAMP response element-binding (CREB) recruitment following a specific CpG - cAMP response element-binding (CREB) recruitment following a specific CpG
Bui C, Barter MJ, Scott JL, Xu Y, Galler M, Reynard LN, Rowan AD, Young DA. FASEB J. 2012 Jul;26(7):3000-11.
Role of Pax3 acetylation in the regulation of Hes1 and Neurog2. - Role of Pax3 acetylation in the regulation of Hes1 and Neurog2.
Ichi S, Boshnjaku V, Shen YW, Mania-Farnell B, Ahlgren S, Sapru S, Mansukhani N, McLone DG, Tomita T, Mayanil CS. Mol Biol Cell. 2011 Feb 15;22(4):503-12.
Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in - Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in
Place AT, Chen Z, Bakhshi FR, Liu G, O'Bryan JP, Minshall RD. Mol Pharmacol. 2011 Oct;80(4):665-72.
Combinatorial patterning of chromatin regulators uncovered by genome-wide - Combinatorial patterning of chromatin regulators uncovered by genome-wide
Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE. Cell. 2011 Dec 23;147(7):1628-39.