Anti-MDC1 antibody
| Name | Anti-MDC1 antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab11170 |
| Prices | $385.00 |
| Sizes | 50 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC-P WB IP |
| Species Reactivities | Human |
| Antigen | Synthetic peptide, which represents a portion of the human Mediator of DNA Damage Checkpoint Protein 1 encoded within exon 8 (LocusLink ID 9656) |
| Description | Rabbit Polyclonal |
| Gene | MDC1 |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling MDC1 with ab11170 at 1/1000 (1µg/ml). Detection: DAB.
IHC image of MDC1 staining in human breast adenocarcinoma formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab11170, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.
Product References
Estrogen receptor alpha-mediated transcription induces cell cycle-dependent DNA - Estrogen receptor alpha-mediated transcription induces cell cycle-dependent DNA
Williamson LM, Lees-Miller SP. Carcinogenesis. 2011 Mar;32(3):279-85.
Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in - Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in
Bu Y, Suenaga Y, Ono S, Koda T, Song F, Nakagawara A, Ozaki T. Genes Cells. 2008 Jan;13(1):53-66.