Anti-MRP1 antibody [MRPm5]
| Name | Anti-MRP1 antibody [MRPm5] |
|---|---|
| Supplier | Abcam |
| Catalog | ab24102 |
| Prices | $394.00 |
| Sizes | 500 µl |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone | MRPm5 |
| Applications | IHC-F IHC-P FC WB ICC/IF |
| Species Reactivities | Rat, Human |
| Antigen | Fusion protein, corresponding to amino acids 986-1204 of Human MRP1 |
| Description | Mouse Monoclonal |
| Gene | ABCC1 |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
ICC/IF image of Anti-MRP1 antibody (ab24102) stained human ES cell derived hepatocytes. The cells were fixed in methanol, blocked and permeabilized using 10% BSA in PBS/0.1% Tween, for 1 hour at 20oC. The cells were then incubated with ab24102 at a 1/50 dilution for 16 hours at 4oC. The secondary antibody was a Donkey anti-Mouse Alexa Fluor 488, used at a 1/400 dilution.See Abreview
![Overlay histogram showing HL60 cells stained with ab24102 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab24102, 0.5µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_3/24458_MRP1-Primary-antibodies-ab24102-7.jpg)
Overlay histogram showing HL60 cells stained with ab24102 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab24102, 0.5µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.
Product References
Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their - Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their
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Molecular-guided therapy predictions reveal drug resistance phenotypes and - Molecular-guided therapy predictions reveal drug resistance phenotypes and
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Differential gene and microRNA expression between etoposide resistant and - Differential gene and microRNA expression between etoposide resistant and
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Variations in ATP-binding cassette transporter regulation during the progression - Variations in ATP-binding cassette transporter regulation during the progression
Hardwick RN, Fisher CD, Canet MJ, Scheffer GL, Cherrington NJ. Drug Metab Dispos. 2011 Dec;39(12):2395-402.
Subcellular localization of transporters along the rat blood-brain barrier and - Subcellular localization of transporters along the rat blood-brain barrier and
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