Anti-PI 3 Kinase p110 delta antibody
| Name | Anti-PI 3 Kinase p110 delta antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab1678 |
| Prices | $394.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | ICC/IF ICC/IF IP WB ELISA ICC/IF |
| Species Reactivities | Mouse, Human |
| Antigen | 20 amino acid C-terminal peptide to Phosphoinositide 3 Kinase p110 delta |
| Description | Rabbit Polyclonal |
| Gene | PIK3CD |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
ICC/IF image of ab1678 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab1678, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.
Product References
Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on - Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on
Yea SS, So L, Mallya S, Lee J, Rajasekaran K, Malarkannan S, Fruman DA. PLoS One. 2014 Jun 10;9(6):e99486.
Inhibition of PI3Kdelta reduces kidney infiltration by macrophages and - Inhibition of PI3Kdelta reduces kidney infiltration by macrophages and
Suarez-Fueyo A, Rojas JM, Cariaga AE, Garcia E, Steiner BH, Barber DF, Puri KD, Carrera AC. J Immunol. 2014 Jul 15;193(2):544-54.
The p110delta isoform of the kinase PI(3)K controls the subcellular - The p110delta isoform of the kinase PI(3)K controls the subcellular
Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno IM, Nock G, Filloux A, Beyaert R, Flamand V, Vanhaesebroeck B. Nat Immunol. 2012 Nov;13(11):1045-54.
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with - Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with
Sanchez CG, Ma CX, Crowder RJ, Guintoli T, Phommaly C, Gao F, Lin L, Ellis MJ. Breast Cancer Res. 2011 Mar 1;13(2):R21.
Inhibition of PI3K prevents the proliferation and differentiation of human lung - Inhibition of PI3K prevents the proliferation and differentiation of human lung
Conte E, Fruciano M, Fagone E, Gili E, Caraci F, Iemmolo M, Crimi N, Vancheri C. PLoS One. 2011;6(10):e24663.
Enhanced phosphoinositide 3-kinase delta activity is a frequent event in systemic - Enhanced phosphoinositide 3-kinase delta activity is a frequent event in systemic
Suarez-Fueyo A, Barber DF, Martinez-Ara J, Zea-Mendoza AC, Carrera AC. J Immunol. 2011 Sep 1;187(5):2376-85.
The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor - The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor
Ramadani F, Bolland DJ, Garcon F, Emery JL, Vanhaesebroeck B, Corcoran AE, Okkenhaug K. Sci Signal. 2010 Aug 10;3(134):ra60.
Phosphoinositide 3-kinase delta regulates membrane fission of Golgi carriers for - Phosphoinositide 3-kinase delta regulates membrane fission of Golgi carriers for
Low PC, Misaki R, Schroder K, Stanley AC, Sweet MJ, Teasdale RD, Vanhaesebroeck B, Meunier FA, Taguchi T, Stow JL. J Cell Biol. 2010 Sep 20;190(6):1053-65.
PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has - PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has
Park S, Chapuis N, Bardet V, Tamburini J, Gallay N, Willems L, Knight ZA, Shokat KM, Azar N, Viguie F, Ifrah N, Dreyfus F, Mayeux P, Lacombe C, Bouscary D. Leukemia. 2008 Sep;22(9):1698-706.