| Name | TMEM88 Antibody |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 254490 |
| Prices | $292.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Applications | ELISA WB |
| Species Reactivities | Human |
| Antigen | KLH-conjugated synthetic peptide encompassing a sequence within human TMEM88. |
| Purity/Format | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| Description | Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner. |
| Gene | TMEM88 |
| Supplier Page | Shop |