| Name | BRCA1 (Rodent) Antibody |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 251302 |
| Prices | $292.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Applications | ELISA IHC WB |
| Species Reactivities | Mouse |
| Antigen | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse BRCA1. |
| Purity/Format | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| Description | Breast cancer type 1 susceptibility protein (BRCA1) is an E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. Defects in BRCA1 are a cause of susceptibility to breast cancer (BC). |
| Gene | Brca1 |
| Supplier Page | Shop |