Anti-Tapasin Related Protein antibody
| Name | Anti-Tapasin Related Protein antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab57411 |
| Prices | $370.00 |
| Sizes | 100 µg |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Applications | WB FC IP |
| Species Reactivities | Human |
| Antigen | Recombinant fragment: PHPAEGQWRA VDVVLDCFLV KDGAHRGALA SSEDRARASL VLKQVPVLDD GSLEDFTDFQ GGTLAQDDPP IIFEASVDLV QIPQAEALLH ADCSGKEVT, corresponding to amino acids 23-122 of Human Tapasin Related Protein Run BLAST with Run BLAST with |
| Description | Mouse Monoclonal |
| Gene | TAPBPL |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
![Overlay histogram showing A431 cells stained with ab57411 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab57411, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_5/8420_Tapasin-Related-Protein-Primary-antibodies-ab57411-1.jpg)
Overlay histogram showing A431 cells stained with ab57411 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab57411, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.
Product References
Tapasin-related protein TAPBPR is an additional component of the MHC class I - Tapasin-related protein TAPBPR is an additional component of the MHC class I
Boyle LH, Hermann C, Boname JM, Porter KM, Patel PA, Burr ML, Duncan LM, Harbour ME, Rhodes DA, Skjodt K, Lehner PJ, Trowsdale J. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3465-70. doi:
The binding of TAPBPR and Tapasin to MHC class I is mutually exclusive. - The binding of TAPBPR and Tapasin to MHC class I is mutually exclusive.
Hermann C, Strittmatter LM, Deane JE, Boyle LH. J Immunol. 2013 Dec 1;191(11):5743-50.