Immunohistochemistry: ROPN1 Antibody - Normal tissues showed moderate to strong cytoplasmic staining. Additional membranous positivity was sometimes seen. Testis, gastro-intestinal tract, parathyroid gland, placenta, spleen and myocytes displayed strong cytoplasmic immunoreactivity. A majority of cancers displayed moderate cytoplasmic staining. Colo-rectal, renal, stomach and liver malignancies exhibited moderate to strong positivity. Gliomas, lymphomas, melanomas, skin and lung cancers were weakly to moderately stained. Image and statement courtesy of the Human Protein Atlas (HPA).