Immunohistochemistry: SETD5 Antibody - Strong cytoplasmic and nuclear staining was observed in glandular cells of the gastrointestinal tract, parathyroid and thyroid glands, adrenal cortex and upper airway epithelium. The remaining normal tissues generally displayed weak to moderate nuclear and/or cytoplasmic positivity. Cells of the liver were negative. Among tumors, most cases showed weak to moderate nuclear and/or cytoplasmic positivity. Some malignant gliomas and malignant carcinoids showed strong nuclear staining. Most renal and endometrial cancers were negative. Image and statement courtesy of the Human Protein Atlas (HPA).