Cleaved Notch1 (Val1744) Antibody
| Name | Cleaved Notch1 (Val1744) Antibody |
|---|---|
| Supplier | Cell Signaling Technology |
| Catalog | 2421 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Species Reactivities | Mouse |
| Antigen | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence at the Val1754 cleavage site in human Notch 1 (equivalent to Val1744 in mouse Notch1) |
| Description | Rabbit Polyclonal |
| Gene | NOTCH1 |
| Supplier Page | Shop |
Product images
Western blot analysis of extracts from 293 cells transfected with full-length Notch1, either untreated or treated with 5 mM EDTA for 15 minutes, and MOLT-4 extracts, using Cleaved Notch 1 (Val1744) Antibody.
Product References
High-level expression of Mastermind-like 2 contributes to aberrant activation of - High-level expression of Mastermind-like 2 contributes to aberrant activation of
Kochert K, Ullrich K, Kreher S, Aster JC, Kitagawa M, Johrens K, Anagnostopoulos I, Jundt F, Lamprecht B, Zimber-Strobl U, Stein H, Janz M, Dorken B, Mathas S. Oncogene. 2011 Apr 14;30(15):1831-40.
Mapping spatio-temporal activation of Notch signaling during neurogenesis and - Mapping spatio-temporal activation of Notch signaling during neurogenesis and
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Notch-1 activation and dendritic atrophy in prion disease. - Notch-1 activation and dendritic atrophy in prion disease.
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GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. - GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides.
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CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, - CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement,
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Inhibition of Dll4 signalling inhibits tumour growth by deregulating - Inhibition of Dll4 signalling inhibits tumour growth by deregulating
Ridgway J, Zhang G, Wu Y, Stawicki S, Liang WC, Chanthery Y, Kowalski J, Watts RJ, Callahan C, Kasman I, Singh M, Chien M, Tan C, Hongo JA, de Sauvage F, Plowman G, Yan M. Nature. 2006 Dec 21;444(7122):1083-7.
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance - FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance
O'Neil J, Grim J, Strack P, Rao S, Tibbitts D, Winter C, Hardwick J, Welcker M, Meijerink JP, Pieters R, Draetta G, Sears R, Clurman BE, Look AT. J Exp Med. 2007 Aug 6;204(8):1813-24. Epub 2007 Jul 23.
Analysis of Notch function in presomitic mesoderm suggests a - Analysis of Notch function in presomitic mesoderm suggests a
Huppert SS, Ilagan MX, De Strooper B, Kopan R. Dev Cell. 2005 May;8(5):677-88.