Anti-DOCK8 antibody produced in rabbit
| Name | Anti-DOCK8 antibody produced in rabbit |
|---|---|
| Supplier | Sigma-Aldrich |
| Catalog | HPA003218 |
| Prices | $429.00 |
| Sizes | 100 µl |
| Host | Rabbit |
| Clonality | Polyclonal |
| Applications | IHC-P WB |
| Species Reactivities | Human |
| Antigen | Dedicator of cytokinesis protein 8 recombinant protein epitope signature tag (PrEST) |
| Description | Rabbit Polyclonal |
| Gene | DOCK8 |
| Conjugate | unconjugated |
| Supplier Page | Shop |
Product images
ImmunohistochemistryAnti-DOCK8: Cat. No. HPA003218: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human placenta tissue showing cytoplasmic staining as well as positive staining of rod-like structures in trophoblastic cells..
ImmunofluorescenceAnti-DOCK8: Cat. No. HPA003218: Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus, nucleus but not nucleoli and cytoplasm.
![<B>Immunoblotting</B><BR/>Anti-DOCK8: <B>Cat. No. HPA003218</B>:<BR/><B>Lanes</B><BR/>1. Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<BR/>2. Negative control (vector only transfected HEK293T lysate)<BR/>3. Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY404295)](http://www.bioprodhub.com/system/product_images/ab_products/7/sub_1/28204_hpa003218-blot-1-l-large.jpg)
ImmunoblottingAnti-DOCK8: Cat. No. HPA003218:
Lanes
1. Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
2. Negative control (vector only transfected HEK293T lysate)
3. Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY404295)
Product References
Homozygous deletion and reduced expression of the DOCK8 gene in human lung - Homozygous deletion and reduced expression of the DOCK8 gene in human lung
Takahashi K, Kohno T, Ajima R, Sasaki H, Minna JD, Fujiwara T, Tanaka N, Yokota J. Int J Oncol. 2006 Feb;28(2):321-8.
Isolation and characterisation of DOCK8, a member of the DOCK180-related - Isolation and characterisation of DOCK8, a member of the DOCK180-related
Ruusala A, Aspenstrom P. FEBS Lett. 2004 Aug 13;572(1-3):159-66.
Combined immunodeficiency associated with DOCK8 mutations. - Combined immunodeficiency associated with DOCK8 mutations.
Zhang Q, Davis JC, Lamborn IT, Freeman AF, Jing H, Favreau AJ, Matthews HF, Davis J, Turner ML, Uzel G, Holland SM, Su HC. N Engl J Med. 2009 Nov 19;361(21):2046-55.
DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell - DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell
Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I, Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G, Dasouki M, Al-Herz W, Barlan I, Baris S, Kutukculer N, Ochs HD, Plebani A, Kanariou M, Lefranc G, Reisli I, Fitzgerald KA, Golenbock D, Manis J, Keles S, Ceja R, Chatila TA, Geha RS. Nat Immunol. 2012 May 13;13(6):612-20.