Anti-MGME1 antibody produced in rabbit

• Supplier: Sigma-Aldrich
• Catalog: HPA040913
• Prices: $429.00
• Sizes: 100 µl
• Host: Rabbit
• Clonality: Polyclonal
• Applications: IHC-P
• Species Reactivities: Human
• Antigen: chromosome 20 open reading frame 72 recombinant protein epitope signature tag (PrEST)
• Description: Rabbit Polyclonal
• Gene: MGME1
• Conjugate: unconjugated

Product images

Immunohistochemistry
Anti-C20orf72: Cat. No. HPA040913: Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.

Immunofluorescence
Anti-C20orf72: Cat. No. HPA040913: Immunofluorescent staining of Human cell line U-2 OS shows positivity in mitochondria.

Immunoblotting
Anti-C20orf72: Cat. No. HPA040913:
Lane
1. Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
2. Human cell line RT-4
3. Human cell line U-251 MG sp

Product References

Loss-of-function mutations in MGME1 impair mtDNA replication and cause - Loss-of-function mutations in MGME1 impair mtDNA replication and cause

Kornblum C, Nicholls TJ, Haack TB, Scholer S, Peeva V, Danhauser K, Hallmann K, Zsurka G, Rorbach J, Iuso A, Wieland T, Sciacco M, Ronchi D, Comi GP, Moggio M, Quinzii CM, DiMauro S, Calvo SE, Mootha VK, Klopstock T, Strom TM, Meitinger T, Minczuk M, Kunz WS, Prokisch H. Nat Genet. 2013 Feb;45(2):214-9.

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 - Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72

Szczesny RJ, Hejnowicz MS, Steczkiewicz K, Muszewska A, Borowski LS, Ginalski K, Dziembowski A. Nucleic Acids Res. 2013 Mar 1;41(5):3144-61.