Description |
Rabbit polyclonal to PRSS1.PRSS1 is also known as Trypsin-1, which belongs to the peptidase S1 family. PRSS1 has activityagainst the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mecand Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all ofthese substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT), a disease characterized bythe presence of calculi in pancreatic ducts and it causes severe abdominal pain attacks.
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