Typical Donor molecule Standard Curve obtained following assay protocol.
Measurement of CETP activity on 1 µL rabbit serum (dark blue diamonds), 1 µL human plasma (orange squares) or 800 ng recombinant human CETP (purple circles). Background control with no serum is shown (green triangles).
Inhibition curve of CETP activity from rabbit serum by Torcetrapib (CETP inhibitor). The assay was run for 1 hour and the IC50 was determined to be 3.56 nM.
Inhibition of CETP activity from human plasma using 80 nM Torcetrapib; assay was run for 2 hours following protocol instructions.