Sunitinib, Malate Salt

Name Sunitinib, Malate Salt
Supplier Biorbyt
Catalog orb61101
Prices $298.00, $340.00, $391.00, $400.00, $638.00, $1,071.00
Sizes 300 mg, 500 mg, 1 g, 2 g, 5 g, 10 g
Cas Number [341031-54-7]
Pubchem 6456015
Chemical Name (Z)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide,(S)-2-hydroxysuccinicacid
Formula C22H27FN4O2•C4H6O5
Molecular Weight 532.56 g/mol
Purity >99% pure
Description Sunitinib Malate (Sutent, SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. A Phase I/II study of Sunitinib in young patients with advanced gastrointestinal stromal tumor is currently ongoing.
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