17-AAG [Out of Stock]

Name 17-AAG [Out of Stock]
Supplier Biorbyt
Catalog orb60994
Prices $264.00, $383.00, $417.00, $468.00, $604.00, $876.00, $1,318.00, $2,083.00, $3,273.00
Sizes 25 mg, 100 mg, 200 mg, 250 mg, 500 mg, 1 g, 2 g, 5 g, 10 g
Cas Number [75747-14-7]
Pubchem 71296110
Chemical Name [(3R,6R,7R,8E,11S,12Z,14E)-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl]carbamate
Formula C31H43N3O8
Molecular Weight 585.69 g/mol
Purity >99% pure
Description 17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50of 5 nM. A Phase II study of 17-AAG in patients with relapsed/refractory CD30 plus anaplastic large cell lymphoma (ALCL) relapsed/refractory mantle cell lymphoma (MCL) and relapsed/refractory classical Hodgkins lymphoma (HL) has been completed. 17-AAG displays significantly low toxicity toward normal cells.
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