Danusertib (PHA-739358)

Name Danusertib (PHA-739358)
Supplier Creative Biomart
Catalog EI-0927
Cas Number 827318-97-8
Chemical Name (R)-N-(5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol -3-yl)-4-(4-methylpiperazin-1-yl)benzamide
Formula C26H30N6O3
Molecular Weight 474.55
Description Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc
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