Semagacestat (LY450139)

Name Semagacestat (LY450139)
Supplier Creative Biomart
Catalog EI-0208
Cas Number 425386-60-3
Chemical Name (S)-2-hydroxy-3-methyl-N-((S)-1-((S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-b enzo[d]azepin-1-ylamino)-1-oxopropan-2-yl)butanamide
Formula C19H27N3O4
Molecular Weight 361.44
Purity >99%
Description Semagacestat (LY450139) can inhibit gamma-secretase such as, Abeta42, Abeta40 and Abeta38, with IC50 of 10.9 nM, 12.1 nM and 12.0 nM.
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