VX-680 (MK-0457,Tozasertib)

• Supplier: Creative Biomart
• Catalog: EI-0913
• Cas Number: 639089-54-6
• Chemical Name: N-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin -2-ylthio)phenyl)cyclopropanecarboxamide
• Formula: C23H28N8OS
• Molecular Weight: 464.59
• Description: VX-680 (MK-0457, Tozasertib) is a pan-Aurora inhibitor, mostly against Aurora A with Kiapp of 0.6 nM, less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases