ENMD-2076

Name ENMD-2076
Supplier Creative Biomart
Catalog EI-0946
Cas Number 934353-76-1
Chemical Name (E)-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimid in-4-amine
Formula C21H25N7
Molecular Weight 375.47
Description ENMD-2076 has selective activity against Aurora A and VEGFR(Flt3) with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα
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