Name | AT101 |
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Supplier | Creative Biomart |
Catalog | EI-0932 |
Cas Number | 866541-93-7 |
Chemical Name | [2,2"-Binaphthalene]-8,8"-dicarboxaldehyde, 1,1",6,6",7,7"-hexahydroxy-3,3"-dimethyl-5,5"-bis(1-methylethyl)-, (2R)-, compd. with acetic acid (1:1) |
Formula | C30H30O8.C2H4O2 |
Molecular Weight | 578.61 |
Description | AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 1/2. |
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