Afatinib (BIBW2992)

Name Afatinib (BIBW2992)
Supplier Creative Biomart
Catalog EI-0048
Cas Number 439081-18-2
Chemical Name (S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinaz olin-6-yl)-4-(dimethylamino)but-2-enamide
Formula C24H25CLFN5O3
Molecular Weight 485.94
Purity >99%
Description BIBW2992 can inhibit EGFR(WT), EGFR(L858R), EGFR(L858R/T790M), and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM.
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