TAK-285

Name TAK-285
Supplier Creative Biomart
Catalog EI-0935
Cas Number 871026-44-7
Chemical Name N-(2-(4-(3-chloro-4-(3-(trifluoromethyl)phenoxy)phenylamino)-5H-pyrrolo[3,2 -d]pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide
Formula C26H25ClF3N5O3
Molecular Weight 547.96
Description TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc
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