MK-2461

• Supplier: Creative Biomart
• Catalog: EI-0940
• Cas Number: 917879-39-1
• Chemical Name: N-((2R)-1,4-Dioxan-2-ylmethyl)-N-methyl-N"-[3-(1-methyl-1H-pyrazol-4-yl)-5- oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide
• Formula: C24H25N5O5S
• Molecular Weight: 495.55
• Description: MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. Phase 1/2..