Tivozanib (AV-951)

• Supplier: Creative Biomart
• Catalog: EI-0065
• Cas Number: 475108-18-0
• Chemical Name: 1-(2-chloro-4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(5-methylisoxazol-3- yl)urea
• Formula: C22H19ClN4O5
• Molecular Weight: 454.86
• Purity: >99%
• Description: Tivozanib (AV-951; KRN-951) is able to markedly inhibit VEGFR-1, VEGFR-2, VEGFR-3, c-Kit and PDGFR with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM.