BIBF1120 (Vargatef)

Name BIBF1120 (Vargatef)
Supplier Creative Biomart
Catalog EI-0070
Cas Number 656247-17-5
Chemical Name (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Formula C31H33N5O4
Molecular Weight 539.62
Purity >99%
Description BIBF 1120 (Vargatef) can inhibit VEGFR1, VEGFR2, VEGFR3, FGFR1, FGFR2, FGFR3, FGFR4, PDGFRalpha, PDGFRbeta, Flt3, Lck, Lyn and Scr with IC50 of 34 nM, 21 nM, 13 nM, 69 nM, 37 nM, 108 nM, 610 nM, 59 nM, 65 nM, 26 nM, 16 nM, 195 nM, and 156 nM.
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