Name | BIBF1120 (Vargatef) |
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Supplier | Creative Biomart |
Catalog | EI-0070 |
Cas Number | 656247-17-5 |
Chemical Name | (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate |
Formula | C31H33N5O4 |
Molecular Weight | 539.62 |
Purity | >99% |
Description | BIBF 1120 (Vargatef) can inhibit VEGFR1, VEGFR2, VEGFR3, FGFR1, FGFR2, FGFR3, FGFR4, PDGFRalpha, PDGFRbeta, Flt3, Lck, Lyn and Scr with IC50 of 34 nM, 21 nM, 13 nM, 69 nM, 37 nM, 108 nM, 610 nM, 59 nM, 65 nM, 26 nM, 16 nM, 195 nM, and 156 nM. |
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