Dovitinib (TKI-258)

• Supplier: Creative Biomart
• Catalog: EI-0073
• Cas Number: 405169-16-6
• Chemical Name: 1-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)qui nolin-2(1H)-one
• Formula: C21H21FN6O
• Molecular Weight: 392.43
• Purity: >99%
• Description: Dovitinib (TKI-258) can inhibit VEGFR1, VEGFR2, VEGFR3, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR3, Flt3, and c-Kit with IC50 of 10 nM, 13 nM, 8 nM, 210 nM, 27 nM, 8 nM, 9 nM, 1 nM and 2 nM.