Cabozantinib malate (XL184)

• Supplier: Creative Biomart
• Catalog: EI-0843
• Cas Number: 1140909-48-3
• Chemical Name: Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N"-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1)
• Formula: C28H24FN3O5.C4H6O5
• Molecular Weight: 635.59
• Description: Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.