| Name | Motesanib Diphosphate (AMG-706) |
|---|---|
| Supplier | Creative Biomart |
| Catalog | EI-0929 |
| Cas Number | 857876-30-3 |
| Chemical Name | 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-, phosphate (1:2) |
| Formula | C22H23N5O.2H3PO4 |
| Molecular Weight | 569.44 |
| Description | Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret |
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