XL-184 free base (Cabozantinib)

• Supplier: Creative Biomart
• Catalog: EI-0056
• Cas Number: 849217-68-1
• Chemical Name: N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane- 1,1-dicarboxamide
• Formula: C28H24FN3O5
• Molecular Weight: 501.51
• Purity: >99%
• Description: As a pan-tyrosine kinase inhibitor, XL-184 (BMS-907351, Cabozantinib) can potently inhibit VEGFR2, Met, Kit, Tie2 and FLT-3 with IC50 of 0.035 nM, 1.8 nM, 4.6 nM, 14.3 nM and 14.4 nM.