Tandutinib (MLN518)

• Supplier: Creative Biomart
• Catalog: EI-0895
• Cas Number: 387867-13-2
• Chemical Name: N-(4-isopropoxyphenyl)-4-(6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin -4-yl)piperazine-1-carboxamide
• Formula: C31H42N6O4
• Molecular Weight: 562.7
• Description: Tandutinib (MLN518, CT53518) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15-to-20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 1/2.