SAR131675

Name SAR131675
Supplier Creative Biomart
Catalog EI-0951
Chemical Name (R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-o xo-1,4-dihydro-1,8-naphthyridine-3-carboxamide
Formula C18H22N4O4
Molecular Weight 358.39
Description SAR131675 is a VEGFR3 inhibitor with IC50/Ki of 23 nM/12 nM, about 50- and 10-fold more selective for VEGFR3 than VEGFR1/2, little activity against Akt1, CDKs, PLK1, EGFR, IGF-1R, c-Met, Flt2 etc.
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