S-Ruxolitinib (INCB018424)

Name S-Ruxolitinib (INCB018424)
Supplier Creative Biomart
Catalog EI-1076
Cas Number 941685-37-6
Chemical Name 1H-Pyrazole-1-propanenitrile, β-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-, (βS)-
Formula C17H18N6
Molecular Weight 306.37
Purity 0.9981
Description S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3
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