Name | JAK2 Inhibitor II |
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Supplier | Creative Biomart |
Catalog | EI-1063 |
Cas Number | 1837-91-8 |
Chemical Name | 1,2,3,4,5,6-Hexabromocyclohexane |
Formula | C6H6Br6 |
Molecular Weight | 557.5 |
Purity | ≥ 97% by GC |
Description | A cell-permeable hexabromocyclohexane compound that interacts with a solvent-accessible pocket near the activation loop of JAK2 and acts as a specific, reversible, and direct inhibitor of JAK2 autophosphorylation (maximal inhibition at 50 μM in BSC-40 cells overexpressing JAK2) |
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