Semaxanib (SU5416)

Name Semaxanib (SU5416)
Supplier Creative Biomart
Catalog EI-0881
Cas Number 194413-58-6
Chemical Name 2H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)-
Formula C15H14N2O
Molecular Weight 238.28
Description Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
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