Name | TAK-715 |
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Supplier | Creative Biomart |
Catalog | EI-1116 |
Cas Number | 303162-79-0 |
Chemical Name | N-(4-(2-ethyl-4-m-tolylthiazol-5-yl)pyridin-2-yl)benzamide |
Formula | C24H21N3OS |
Molecular Weight | 399.51 |
Purity | > 95% |
Description | TAK-715 is a potent specific inhibitor of the p38α MAP kinase with an IC50 value of 7.1 nM. It inhibited TNF-α production by 87.6% in mice at 10 mg/kg, po and has potential for treatment of TNF-α mediated inflammatory diseases such as rheumatoid arthriti. |
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