TAK-715

Name TAK-715
Supplier Creative Biomart
Catalog EI-1116
Cas Number 303162-79-0
Chemical Name N-(4-(2-ethyl-4-m-tolylthiazol-5-yl)pyridin-2-yl)benzamide
Formula C24H21N3OS
Molecular Weight 399.51
Purity > 95%
Description TAK-715 is a potent specific inhibitor of the p38α MAP kinase with an IC50 value of 7.1 nM. It inhibited TNF-α production by 87.6% in mice at 10 mg/kg, po and has potential for treatment of TNF-α mediated inflammatory diseases such as rheumatoid arthriti.
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