GNF-5837

Name GNF-5837
Supplier Creative Biomart
Catalog EI-1158
Cas Number 1033769-28-6
Chemical Name (Z)-1-(3-((3-((1H-pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)amino)-4-methylp henyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
Formula C28H21F4N5O2
Molecular Weight 535.49
Purity > 95%
Description GNF-5837 is a potent, selective and orally bioavailable pan-TRK inhibitor of TRKA, TRKB and TRKC with the IC50 of 11nM, 9nM and 7nM, respectively.
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