Name | NSC 23766 |
---|---|
Supplier | Creative Biomart |
Catalog | EI-0640 |
Cas Number | 733767-34-5 |
Chemical Name | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride |
Formula | C??H??N?.3HCl |
Molecular Weight | 298.29 |
Purity | ≥97% by TLC |
Description | A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam 1 (IC50 = 50 μM) without affecting the closely related GTPases, Cdc42, and RhoA activation |
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