NSC 23766

Name NSC 23766
Supplier Creative Biomart
Catalog EI-0640
Cas Number 733767-34-5
Chemical Name N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
Formula C??H??N?.3HCl
Molecular Weight 298.29
Purity ≥97% by TLC
Description A cell-permeable, reversible, and selective Rac1 inhibitor; inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam 1 (IC50 = 50 μM) without affecting the closely related GTPases, Cdc42, and RhoA activation
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