Name | PF-4708671 |
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Supplier | Creative Biomart |
Catalog | EI-0866 |
Cas Number | 1255517-76-0 |
Chemical Name | 1H-Benzimidazole, 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)- |
Formula | C19H21F3N6 |
Molecular Weight | 390.41 |
Description | PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity FOR S6K1than MSK1 and RSK1/2, respectively |
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