Name | HDL Receptor SR-BI Inhibitor, BLT-1 - CAS 321673-30-7 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 373210 |
Cas Number | 321673-30-7 |
Formula | C₁₂H₂₃N₃S |
Purity | ≥95% by HPLC |
Description | A cell-permeable thiosemicarbazone copper chelator that potently blocks the HDL receptor SR-BI- (scavenger receptor, class B, type I) mediated lipid uptake (IC 50 = 21 and 57 nM against DiI and CE uptake, respectively, from DiI-HDL and CE-HDL using hamster ldlA-7 cells expressing murine SR-BI) in a reversible manner, while exerting little effect toward intracellular membrane trafficking or cytoskeletal organization |
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