Name | Cytoplasmic Dynein Inhibitor, Ciliobrevin D - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 250401 |
Formula | C₁₇H₈Cl₃N₃O₂ |
Purity | ≥99% by HPLC |
Description | A cell-permeable benzoyl dihydroquinazolinone derivative that acts as a reversible and specific blocker of AAA+ ATPase motor cytoplasmic dynein and disrupts spindle pole focusing, cold-stable microtubule formation, kinetochore-microtubule attachment, and melanosome aggregation in a dose-dependent manner (~10 to 40 µM) |
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