CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem

Name CBFβ Inhibitor - CAS 493028-20-9 - Calbiochem
Supplier EMD Millipore
Catalog 219505
Cas Number 493028-20-9
Formula C₁₂H₁₄N₂OS
Purity ≥97% by HPLC
Description A cell-permeable thiazolyl compound that binds to CBFβ (core binding factor β) and allosterically disrupts CBFα/Runx1 binding to CBFβ both in cell-free binding studies (IC 50 of ~3.5 µM by FRET and ELISA) and in HEK293 cells (IC 50 of ~100 µM by FACS/FRET)
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