Cdk4/6 Inhibitor IV - CAS 359886-84-3 - Calbiochem
| Name | Cdk4/6 Inhibitor IV - CAS 359886-84-3 - Calbiochem |
|---|---|
| Supplier | EMD Millipore |
| Catalog | 219492 |
| Cas Number | 359886-84-3 |
| Formula | C₂₇H₃₂N₆O |
| Purity | ≥95% by HPLC |
| Description | A cell-permeable triaminopyrimidine compound that acts as a reversible and ATP-competitive inhibitor against Cyclin D1-complexed, but not Cyclin D2-complexed, Cdk4 and Cdk6 (IC 50 = 1.5 & 5.6 µM, respectively) with much reduced activity against Cdk5/p35 (IC 50 = 25 µM) and little or no activity towards Cdk1/CycB, Cdk2/CycA, Cdk2/CycE, v-abl, c-met, IGF-1R, or IR (IC 50 >10 µM) |
| Supplier Page | Shop |
Product images
