Name | PTK/PI 3-K/mTOR Inhibitor, PP121 - CAS 1092788-83-4 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 529584 |
Cas Number | 1092788-83-4 |
Formula | C₁₇H₁₇N₇ |
Purity | ≥98% by HPLC |
Description | A cell-permeable pyrazolopyrimidine compound that effectively targets the ATP pocket of both protein tyrosine kinases (IC 50 <0.26 µM against Abl, EGFR, EphB4, Hck, PDGFR, RET, Src, Src T338I , and VEGFR2) and PI 3-K family kinases (IC 50 <1.4 µM against p110α/ β/ δ/ γ, mTOR, and DNA-PK) |
Supplier Page | Shop |