Name | RXRα Inhibitor, K-80003 - Calbiochem |
---|---|
Supplier | EMD Millipore |
Catalog | 557451 |
Formula | C₂₃H₂₃FO₂ |
Purity | ≥95% by HPLC |
Description | A cell permeable, Sulindac analog with IC 50 =2.4 µM for RXRα binding, and unlike other NSAIDs, is inactive toward COX2 and COX1 even at 1 mM. The compound displays potent inhibition of RXRα dependent AKT Activation in both PC3 and A549 cells, and is RXRα but not RXRγ expression dependent as shown in PC3 cells |
Supplier Page | Shop |