PI 3-Kγ Inhibitor VII - CAS 6318-41-8 - Calbiochem

Name PI 3-Kγ Inhibitor VII - CAS 6318-41-8 - Calbiochem
Supplier EMD Millipore
Catalog 528114
Cas Number 6318-41-8
Formula C₁₁H₇NO₄S
Purity ≥98% by HPLC
Description A cell-permeable thiazolidinedione compound that acts as a potent, ATP-competitive, and isoform-selctive PI 3-K inhibitor (IC 50 = 0.07, 0.24, 1.45, and 1.70 µM for the γ, α, β, and δ isoform, respectively) with little or no activity against a panel of 38 other commonly studied kinases (<20% inhibition at 1.0 µM)
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