Name | PI 3-Kγ Inhibitor VII - CAS 6318-41-8 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 528114 |
Cas Number | 6318-41-8 |
Formula | C₁₁H₇NO₄S |
Purity | ≥98% by HPLC |
Description | A cell-permeable thiazolidinedione compound that acts as a potent, ATP-competitive, and isoform-selctive PI 3-K inhibitor (IC 50 = 0.07, 0.24, 1.45, and 1.70 µM for the γ, α, β, and δ isoform, respectively) with little or no activity against a panel of 38 other commonly studied kinases (<20% inhibition at 1.0 µM) |
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