Name | InSolution™ HIF-1 Inhibitor - CAS 934593-90-5 - Calbiochem |
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Supplier | EMD Millipore |
Catalog | 400092 |
Cas Number | 934593-90-5 |
Formula | A25mM(5mg/459µL)solutionofHIF-1Inhibitor(Cat. |
Purity | ≥95% by HPLC |
Description | A cell-permeable amidophenolic compound that inhibits hypoxia-induced HIF-1 transcription activity (IC 50 = 0.7 and 2.6 µM using AGS and Hep3B cells, respectively, in a reporter assay) by selectively blocking the hypoxia-induced accumulation of cellular HIF-1α protein, while exhibiting no apparent effect on the cellular level of HIF-1α mRNA or that of HIF-1β protein. |
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